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TCCI Investigator Jintai Yu’s Team Publishes First Study on Correlation between Serum Clinical Laboratory Tests and Dementia
Recently, Jintai Yu, professor at Fudan University-affiliated Huashan Hospital and a researcher at the Tianqiao and Chrissy Chen Institute (TCCI), published a study titled “Serum clinical laboratory tests and risk of incident dementia: a prospective cohort study of 407190 individuals” in Translational Psychiatry. The study was designed to investigate the association of common serum laboratory […]
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Friend or Foe? How Mice Decide to Make Love or War
Dog owners whose pets meet during a walk are familiar with the immediate sniffing investigation that typically ensues. Initially, the owners cannot tell whether their dogs will wind up fighting, playing, or trying to mount each other. Something is clearly happening in the dog’s brain to make it decide how to behave toward the other […]
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TCCI Investigator Jintai Yu’s Team Reveals Distribution and Risk Factors of Alzheimer’s Disease Continuum in Northern Chinese Han Population
Recently, Jintai Yu, Professor at Fudan University-affiliated Huashan Hospital and Investigator at Tianqiao and Chrissy Chen Institute, published a paper titled Application of the Amyloid/Tau/Neurodegeneration Framework in Cognitively Intact Adults: The CABLE Study in the journal Annals of Neurology. The study aims to reveal the distribution and risk factors of Alzheimer’s Disease (AD) continuum in […]
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How Fruit Flies Sniff Out Their Environments
Fruit flies—Drosophila melanogaster—have a complicated relationship with carbon dioxide. In some contexts, CO2 indicates the presence of tasty food sources as sugar-fermenting yeast in fruit produces the molecule as a by-product. But in other cases, CO2 can be a warning to stay away, signaling an oxygen-poor or overcrowded environment with too many other flies. How […]
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Caltech to Study How the Brain Responds to Virtual Environments
The rise of social media has meant that social and professional interactions are increasingly carried out online. This trend is expected to continue in the coming decades, as the digital world becomes more immersive and realistic. To understand how the human brain might be affected by this shift, Dean Mobbs, professor of cognitive neuroscience, is […]
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Cell Reports: Wei Lu and Tifei Yuan Collaborate on Research in New Mechanism behind Synaptic Plasticity and Memory Consolidation
August 16, 2022. A research group led by Dr. Wei Lu from Fudan University and Southeast University collaborated with a group led by Tifei Yuan, a Tianqiao and Chrissy Chen Institute Investigator, professor at Shanghai Jiao Tong University and doctoral supervisor at Shanghai Mental Health Center, to publish a paper in Cell Reports titled Trafficking […]
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A Large-Scale Prospective Cohort Study on Dementia Reveals Three Cups of Tea Per Day Produces the Strongest Protective Effect
Dementia is an important public health concern with about 55 million cases worldwide and an incidence of more than 10 million new cases each year. Dementia has become a major cause of disability, dependency and mortality among older people. Emerging research, from animal experiments and cohort studies, however, indicates that drinking either green or black […]
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Automated intraoperative central sulcus localization and somatotopic mapping using median nerve stimulation
The central sulcus (CS) is an important landmark in the brain that delineates functional cortical regions essential in neurological resection or surgery. Dr. Gerwin Schalk, Director of the Chen Frontier Lab for Applied Neurotechnology, and a team of scientists and researchers from other universities developed a new, automated procedure that uses median nerve stimulation (MNS) […]
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Cataracts May Increase Risk of Incident Dementia: A Prospective Cohort Study by Chinese Scholars
Are cataracts associated with dementia? Chinese scholars discovered through a prospective cohort study of more than 300,000 participants that cataracts can lead to structural changes and a reduction in size of the hippocampus, an important brain region associated with the visual cortex and cognition. Their research indicated that timely surgical treatment for cataract patients is […]
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Good Sleep, More Physical Activity, Fewer Sedentary Behaviors Can Reduce Risk of Dementia by 41%: A Cohort Study
Chinese medical experts discovered through a cohort study including more than 430,000 participants (median follow-up 9.0 years) that a combination of seven hours of sleep/day, moderate-to-high leisure-time physical activity (LPTA), and low-to-moderate sedentary behavior can reduce the risk of dementia by 41%. These three types of regulatory behaviors have a combined effect over the risk […]