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Inaugural Chen Institute Brain and Mind Lecture: Dr Adam Gazzaley
The Chen Institute Brain & Mind Lecture series is an annual event at the California Academy of Sciences that explores brain science and mind health in our rapidly changing world. For the inaugural lecture, A New Era of Experiential Medicine: Technology to Enhance Cognition, UCSF’s Dr. Adam Gazzaley described his research on integrating technology […]
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Monitoring of Intra-Tumoral Drug Pharmacokinetics In Vivo With Implantable Sensors
Summary Drug discovery is costly, with only about 10% of drugs in Phase 1 trials gaining FDA approval, largely due to poor understanding of pharmacokinetics (PK). Standard blood-based PK measurements don’t accurately reflect drug levels in tumor tissues, which have complex microenvironments. A team led by Professor Hyongsok Tom Soh developed an implantable electrochemical aptamer-based […]
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eWEAR: Monitoring of Intra-Tumoral Drug Pharmacokinetics In Vivo With Implantable Sensors
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Nanostructured Electrodes Improve Sensor Sensitivity with Faster Electron Transfer
Summary Electrochemical sensors convert chemical signals from target analytes into electrical signals for detection, making them valuable for biomedical applications. Sensitivity is crucial as clinical biomarkers are often present at very low levels, and electrochemical sensors help monitor drug concentrations like doxorubicin in biofluids. A team led by Professor Hyongsok Tom Soh at Stanford developed […]
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eWEAR: Nanostructured Electrodes Improve Sensor Sensitivity with Faster Electron Transfer
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Implantable device for wirelessly controlled drug delivery
Summary Researchers from Stanford University have developed an implantable, ultrasound-powered drug delivery device that integrates nanoparticles and electronics for targeted, on-demand drug release. The device uses a potentiostat to control drug release by measuring the current between electrodes, and it operates wirelessly through ultrasound, making it ideal for deep tissue implantation. The system allows precise […]
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eWEAR: Implantable device for wirelessly controlled drug delivery
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Stanford scientists uncover how brain regions keep each other on track
Summary Before smartphones, memorizing phone numbers was a common necessity, often accomplished by mentally repeating the number. The brain similarly solves short-term memory problems by maintaining patterns of neuronal activity. Researchers, led by Professors Shaul Druckmann and Nuo Li, studied how this occurs in mice by engaging their short-term memory. They discovered that two brain […]
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eWEAR: Stanford scientists uncover how brain regions keep each other on track
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A Window into Maternal Health Through Hair Cortisol
Summary Hair cortisol concentration (HCC) offers a promising non-invasive method to track stress hormone levels over time, particularly during pregnancy. Cortisol, crucial in the body’s stress response, is deposited into hair, reflecting past hormone levels. A study led by Dr. Lucy King at Stanford University examined HCC dynamics in pregnant women and postpartum, finding significant […]