Summary Drug discovery is costly, with only about 10% of drugs in Phase 1 trials gaining FDA approval, largely due to poor understanding of pharmacokinetics (PK). Standard blood-based PK measurements don’t accurately reflect drug levels in tumor tissues, which have complex microenvironments. A team led by Professor Hyongsok Tom Soh developed an implantable electrochemical aptamer-based […]

Summary Electrochemical sensors convert chemical signals from target analytes into electrical signals for detection, making them valuable for biomedical applications. Sensitivity is crucial as clinical biomarkers are often present at very low levels, and electrochemical sensors help monitor drug concentrations like doxorubicin in biofluids. A team led by Professor Hyongsok Tom Soh at Stanford developed […]

Summary Researchers from Stanford University have developed an implantable, ultrasound-powered drug delivery device that integrates nanoparticles and electronics for targeted, on-demand drug release. The device uses a potentiostat to control drug release by measuring the current between electrodes, and it operates wirelessly through ultrasound, making it ideal for deep tissue implantation. The system allows precise […]

Summary Before smartphones, memorizing phone numbers was a common necessity, often accomplished by mentally repeating the number. The brain similarly solves short-term memory problems by maintaining patterns of neuronal activity. Researchers, led by Professors Shaul Druckmann and Nuo Li, studied how this occurs in mice by engaging their short-term memory. They discovered that two brain […]