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Common Drugs Tied to Increased Risk of Cognitive Decline
A class of drugs used for many conditions, including allergies, colds, high blood pressure and depression, may be associated with an increased risk of developing mild thinking and memory problems, particularly in people who have genetic risk factors for Alzheimer’s disease or markers of this condition, according to a study published in the September 2, […]
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MSK Study Links Inflammation to Alzheimer’s Disease Development
Alzheimer’s disease is a neurodegenerative condition that is characterized by the buildup of clumps of beta-amyloid protein in the brain. Exactly what causes these clumps, known as plaques, and what role they play in disease progression is an active area of research important for developing prevention and treatment strategies.
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Small set of genes may provide unique barcode for different types of brain cells in worms
When it comes to brain cells, one size does not fit all. Neurons come in a wide variety of shapes, sizes, and contain different types of brain chemicals. But how did they get that way? A new study in Nature suggests that the identities of all the neurons in a worm are linked to unique […]
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Toddlers who use touchscreens show attention differences
Toddlers with high daily touchscreen use are faster to find targets that stood out during visual search compared to toddlers with no or low touchscreen use – according to new research.
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Researchers find way to speed up nerve regrowth
A University of Alberta researcher has found a treatment that increases the speed of nerve regeneration by three to five times, which may one day lead to much better outcomes for trauma surgery patients.
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研究发现加速神经生长的新方法
在肢体神经移植的过程中,时间是决定成败的一个关键因素。如果神经不能以足够快的速度生长至指定肌肉位置,那么移植就会失败。这也是为什么下肢远端神经移植比上肢神经移植成功率低的原因。而该研究则发现,在进行移植前一周花一小时以20赫兹的频率刺激所需移植的神经可以使其在移植后的生长速度快上3-5倍。虽然此次的研究只进行了将胫神经束移至腓总神经残端以治疗足下垂的实验,但据称,这种电刺激法可适用于周围神经系统中的任何部位。使用该方法我们就可以以人为的手段扩大神经再生的无限潜力。
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“Jumping” DNA regulates human neurons
The human genome contains over 4.5 million sequences of DNA called “transposable elements”, these virus-like entities that “jump” around and help regulate gene expression. They do this by binding transcription factors, which are proteins that regulate the rate of transcription of DNA to RNA, influencing gene expression in a broad range of biological events.
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A tailor-made molecule that ties nerve connections
Synthetic compound could serve as prototype for a novel class of drugs to treat neurological damage.Researchers from the German Center for Neurodegenerative Diseases (DZNE), UK and Japan have developed a neurologically acting protein and tested it in laboratory studies. In mice, the experimental compound ameliorated symptoms of certain neurological injuries and diseases, while on the […]
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Researchers Discover a Specific Brain Circuit Damaged by Social Isolation During Childhood
Loneliness is recognized as a serious threat to mental health. Even as our world becomes increasingly connected over digital platforms, young people in our society are feeling a growing sense of isolation. The COVID-19 pandemic, which forced many countries to implement social distancing and school closures, magnifies the need for understanding the mental health consequences […]
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How brain flexibility emerges in infants
Scientists say they’ve discovered that cognitive flexibility, a critical higher order brain function, starts developing during the first two years of life.Having cognitive flexibility – the mental capacity to switch between different concepts – is associated with better reading ability, academic achievement, resilience and creativity, while less mental suppleness is linked to risk of neurological […]