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“Invisible” Cell Types and Gene Expression Revealed with Sequencing Data Analysis Improvement
In 2018, researchers in the Caltech laboratory of Yuki Oka, Chen Scholar, professor of biology and Heritage Medical Research Institute Investigator, made a major discovery: they identified a type of neuron, or brain cell, that mediates thirst satiation. But they were running into a problem: a state-of-the-art technique called single-cell RNA sequencing (scRNA-seq) could not […]
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Reconstructing Music from Human Auditory Cortex Activity Using Nonlinear Decoding Models
Music is core to the human experience yet the precise neural dynamics underlying music perception remain unknown. Dr. Gerwin Schalk, Director of the Chen Frontier Lab for Neurotechnology was part of a team of researchers who analyzed a unique intracranial electroencephalography (iEEG) dataset of 29 patients who listened to a Pink Floyd song and applied […]
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Huashan Hospital Maps Dementia Risk Factors; Active Interventions can Prevent 47%-73% of Dementia Cases
A study, recently published in the journal Nature Human Behavior (IF: 30) by the clinical research team of Prof. Yu Jintai from the Department of Neurology at Fudan University-affiliated Huashan Hospital, comprehensively mapped the modifiable risk factors for dementia for the first time. The research explored their joint effect on dementia and predicted that 47% […]
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Spatio-temporal evolution of human neural activity during visually cued hand movements
Making hand movements in response to visual cues is common in daily life. It has been well known that this process activates multiple areas in the brain, but how these neural activations progress across space and time remains largely unknown. Taking advantage of intracranial electroencephalographic (iEEG) recordings using depth and subdural electrodes from 36 human […]
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TCCI Hosts Global Competition for Universities to Promote “AI for Brain Science” – The First Stop at Tongji University Kicks Off Today
After announcing an additional ¥1 billion (about US $6.8 million) investment in “AI for Brain Science,” Tianqiao and Chrissy Chen Institute (TCCI) unveils new program to support to university students. On July 18, TCCI officially launched the global competition themed “AI for Brain Science” with Tongji University as the first stop. Focusing on AI-empowered brain […]
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Unexpected sound omissions are signaled in human posterior superior temporal gyrus: an intracranial study
Our brains are excellent at making predictions about what we should hear next, based on context. These predictions help us understand and interact with our surroundings. For example, when listening to a melody, we may predict the next note in a sequence. Dr. Gerwin Schalk, Director of the Chen Frontier Lab for Applied Neurotechnology, and […]
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2023 TCCI Summer Newsletter
Happy summer! We are very happy to share with you an overview of the many things that have been happening at TCCI over the last few months.
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Scientists Create Embryo-Like Model that Mimics Post-Implantation Stage of Human Development
The human body and all its complexity arise from just a small collection of cells that divide and morph into different types of tissues. But exactly how this occurs is hard to study because embryos are hidden inside their mothers. Some embryos are donated to science by individuals who have undergone in vitro fertilization, but […]
