Professor Ying Mao from Huashan Hospital Is First to Validate that Chronic Cerebral Hypoperfusion Can Independently Cause Changes in Alzheimer’s Biomarkers in Moyamoya Disease


Recently, Professor Ying Mao, President of Fudan University-affiliated Huashan Hospital and Director of TCCI Translational Center, recently published a research paper titled “Brain perfusion, cognition, and plasma Alzheimer’s biomarkers in moyamoya disease” in collaboration with his research team in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association (IF:16.655/Q1), a top international journal on neurology. It was validated for the first time in a clinical cohort that the chronic cerebral hypoperfusion can independently cause abnormalities in Alzheimer’s markers, and that the abnormal levels are correlated with the degree of accumulation of hypoperfusion.

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