Diagnosing Parkinson’s disease with skin samples could lead to earlier detection


New research shows a simple skin test can accurately identify Parkinson’s disease, demonstrating for the first time the feasibility of the method. Currently diagnosed by clinical signs and symptoms but only definitively diagnosed at autopsy, Parkinson’s disease is commonly misdiagnosed early in the disease course, complicating clinical trials of potential treatments.

The study, published in the scientific journal Movement Disorders, shows how a chemical assay can detect clumping of the protein alpha-synuclein in skin samples to help diagnose Parkinson’s disease (PD). The study’s authors said using the assay can lead to earlier detection of PD and better clinical trials.