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New marker for early diagnosis of Alzheimer’s disease
An international, multicenter study led by Professor Jintai Yu, a researcher at the Tianqiao and Chrissy Chen Institute and a professor of neurology at Fudan University-affiliated Huashan Hospital, has found that increased volume of the sublateral ventricles is a genetic imaging marker of Alzheimer’s disease, and can be used to predict the risk of Alzheimer’s […]
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New neurosurgical technique: deep brain tumor resection with 3D exoscopy
A team led by Mao Ying, president of Fudan University-affiliated Huashan Hospital and director of the TCCI Translational Center, and Professor Zhu Wei from the Neurosurgery Department of Fudan University-affiliated Huashan Hospital, reported 25 cases of pineal region tumor resection with 3D exoscopy via infratentorial approach, which achieved satisfactory clinical outcomes. Neurosurgery has always been […]
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Stanford Researchers Develop Molecularly Imprinted Polymers for Continual, Real-time Sensing of Dopamine for Health Monitoring
In a recent paper published in ACS Nano, a team of researchers led by Professor Nicholas Melosh and Dr. Nofar Mintz Hemed in the Department of Materials Science and Engineering at Stanford University describe their innovative, dopamine-binding molecularly imprinted polymers (MIP) that have a limit of detection in the sub-nanomolar range and does not require […]
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Unique evolutionary pathways during recurrence of different gliomas
Glioma recurrence has long plagued patients and neurosurgeons however with the development of molecular diagnosis of glioma, research recently published in the journal Nature, has become increasingly precise. A recent study by Mao Ying, President of Fudan University-affiliated Huashan Hospital and Director of TCCI Translational Center, and Professor Hua Wei from the Neurosurgery Department of […]
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Drug Delivery Platform Uses Sound for Targeting
Chemotherapy as a treatment for cancer is one of the major medical success stories of the 20th century, but it’s far from perfect. Anyone who has been through chemotherapy or who has had a friend or loved one go through it will be familiar with its many side effects: hair loss, nausea, weakened immune system, […]
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“Invisible” Cell Types and Gene Expression Revealed with Sequencing Data Analysis Improvement
In 2018, researchers in the Caltech laboratory of Yuki Oka, Chen Scholar, professor of biology and Heritage Medical Research Institute Investigator, made a major discovery: they identified a type of neuron, or brain cell, that mediates thirst satiation. But they were running into a problem: a state-of-the-art technique called single-cell RNA sequencing (scRNA-seq) could not […]
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Reconstructing Music from Human Auditory Cortex Activity Using Nonlinear Decoding Models
Music is core to the human experience yet the precise neural dynamics underlying music perception remain unknown. Dr. Gerwin Schalk, Director of the Chen Frontier Lab for Neurotechnology was part of a team of researchers who analyzed a unique intracranial electroencephalography (iEEG) dataset of 29 patients who listened to a Pink Floyd song and applied […]
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Huashan Hospital Maps Dementia Risk Factors; Active Interventions can Prevent 47%-73% of Dementia Cases
A study, recently published in the journal Nature Human Behavior (IF: 30) by the clinical research team of Prof. Yu Jintai from the Department of Neurology at Fudan University-affiliated Huashan Hospital, comprehensively mapped the modifiable risk factors for dementia for the first time. The research explored their joint effect on dementia and predicted that 47% […]
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Spatio-temporal evolution of human neural activity during visually cued hand movements
Making hand movements in response to visual cues is common in daily life. It has been well known that this process activates multiple areas in the brain, but how these neural activations progress across space and time remains largely unknown. Taking advantage of intracranial electroencephalographic (iEEG) recordings using depth and subdural electrodes from 36 human […]
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Unexpected sound omissions are signaled in human posterior superior temporal gyrus: an intracranial study
Our brains are excellent at making predictions about what we should hear next, based on context. These predictions help us understand and interact with our surroundings. For example, when listening to a melody, we may predict the next note in a sequence. Dr. Gerwin Schalk, Director of the Chen Frontier Lab for Applied Neurotechnology, and […]