Category: Mental disorders

  • Low levels of choline in pregnant Black American women associated with higher levels of stress

    Researchers at the University of Colorado Anschutz Medical Campus have found that many pregnant Black Americans have low levels of choline, an essential nutrient that aids in prenatal brain development. Stress caused by institutional racism may play a role. The study, out now in Schizophrenia Bulletin, also found that these low levels of choline were […]

  • New Study Reveals Brain Circuit Biomarkers to Predict Response to Treatment in Patients with Complex Neuropsychiatric Disorders

    Cohen Veterans Bioscience (CVB), a non-profit research biotech advancing brain health solutions, today announces findings from a study which generates new evidence in support of a critical brain imaging biomarker, that may help guide people who suffer from post-traumatic stress disorder (PTSD) or major depressive disorder (MDD) towards the most effective treatment. The study, entitled […]

  • UMD-Led Study Shows Fear and Anxiety Share Same Bases in Brain

    Anxiety, the most common family of mental illnesses in the U.S., has been pushed to epic new heights by the COVID-19 pandemic, with the Centers for Disease Control and Prevention estimating that nearly 1 in 3 U.S. adults and a staggering 41% of people ages 18-29 experienced clinically significant anxiety symptoms in late August. Now, […]

  • Astrocytes build synapses after cocaine use in mice

    Drugs of abuse, like cocaine, are so addictive due in part to their cellular interaction, creating strong cellular memories in the brain that promote compulsive behaviors. Researchers have tried to understand the formation of these memories in hopes of finding ways to disrupt them as a potential treatment for substance use disorder (SUD). A new […]

  • Study Reveals Most Effective Drugs for Common Type of Neuropathic Pain

    More than 20 million people in the U.S. suffer neuropathic pain. At least 25% of those cases are classified as unexplained and considered cryptogenic sensory polyneuropathy (CSPN). There is no information to guide a physician’s drug choices to treat CSPN, but a researcher from the University of Missouri School of Medicine and MU Health Care […]

  • Nerves that Sense Touch May Play Role in Autism

    Autism is considered a disorder of the brain. But a new study suggests that the peripheral nervous system, the nerves that control our sense of touch, pain and other sensations, may play a role as well. “More than 70% of people with autism have differences in their sensory perception,” said study author Sung-Tsang Hsieh, M.D., […]

  • STAT3 identified as important factor in emotional reactivity

    Numerous scientific studies indicate that inflammatory processes play a key role in the development of psychiatric disorders. One of the areas of particular interest is the interleukin 6/STAT3 signal transduction pathway, which is associated with depression, schizophrenia, and bipolar disorder. In a study published in leading journal Molecular Psychiatry, MedUni Vienna researchers led by Daniela […]

  • New Perspectives to Treat Neuropsychiatric Diseases

    Researchers at the Institute of Biology, Eötvös Loránd University (ELTE), Budapest, Hungary, studied the major types of neurons of the prefrontal cortex of the brain in an international collaboration. The research team has identified molecular differences in neurons that may support drug development for the treatment of psychiatric disorders such as schizophrenia or depression.

  • New clues about the link between stress and depression

    Researchers at Karolinska Institutet have identified a protein in the brain that is important both for the function of the mood-regulating substance serotonin and for the release of stress hormones, at least in mice. The findings, which are published in the journal Molecular Psychiatry, may have implications for the development of new drugs for depression […]

  • Millimetre-precision drug delivery to the brain

    Focused ultrasound waves help ETH researchers to deliver drugs to the brain with pinpoint accuracy, in other words only to where their effect is desired. This method is set to enable treatment of psychiatric and neurological disorders and tumours with fewer side effects in the future.