Neural development continues throughout life in the mammalian brain. TCCI is happy to support this conference which will bring together leaders from diverse fields, such as embryonic cortical development, adult neurogenesis, patient-derived stem cell-based 2D and 3B brain organoid disease modelling, direct reprograming and transplantation to discuss recent advances and remaining gaps in the understanding of the cellular and molecular mechanisms regulating neural stem cell activity, neural fate specification and functional significance of circuitries modified by the addition of new neurons in health and diseases.